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The Ubiquitin-specific Protease USP36 Associates with the Microprocessor Complex and Regulates miRNA Biogenesis by SUMOylating DGCR8

miRNA biogenesis is a cellular process that produces mature miRNAs from their primary transcripts, pri-miRNAs, via two RNAse III enzyme complexes: the Drosha-DGCR8 microprocessor complex in the nucleus and the Dicer-TRBP complex in the cytoplasm. Emerging evidence suggests that miRNA biogenesis is t...

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Detalles Bibliográficos
Autores principales: Li, Yanping, Carey, Timothy S., Feng, Catherine H., Zhu, Hong-Ming, Sun, Xiao-Xin, Dai, Mu-Shui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026737/
https://www.ncbi.nlm.nih.gov/pubmed/36950067
http://dx.doi.org/10.1158/2767-9764.CRC-22-0344