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Enhanced therapeutic efficacy of doxorubicin against multidrug-resistant breast cancer with reduced cardiotoxicity

Doxorubicin (DOX), a commonly used anti-cancer drug, is limited by its cardiotoxicity and multidrug resistance (MDR) of tumor cells. Epigallocatechin gallate (EGCG), a natural antioxidant component, can effectively reduce the cardiotoxicity of DOX. Meanwhile, EGCG can inhibit the expression of P-gly...

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Detalles Bibliográficos
Autores principales: Zhang, Tianyu, Li, Nuannuan, Wang, Ru, Sun, Yiying, He, Xiaoyan, Lu, Xiaoyan, Chu, Liuxiang, Sun, Kaoxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026743/
https://www.ncbi.nlm.nih.gov/pubmed/36919676
http://dx.doi.org/10.1080/10717544.2023.2189118