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Block catiomers with flanking hydrolyzable tyrosinate groups enhance in vivo mRNA delivery via π–π stacking-assisted micellar assembly

Messenger RNA (mRNA) therapeutics have recently demonstrated high clinical potential with the accelerated approval of SARS-CoV-2 vaccines. To fulfill the promise of unprecedented mRNA-based treatments, the development of safe and efficient carriers is still necessary to achieve effective delivery of...

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Detalles Bibliográficos
Autores principales: Yang, Wenqian, Miyazaki, Takuya, Nakagawa, Yasuhiro, Boonstra, Eger, Masuda, Keita, Nakashima, Yuki, Chen, Pengwen, Mixich, Lucas, Barthelmes, Kevin, Matsumoto, Akira, Mi, Peng, Uchida, Satoshi, Cabral, Horacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026751/
https://www.ncbi.nlm.nih.gov/pubmed/36950277
http://dx.doi.org/10.1080/14686996.2023.2170164