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The implication of Mycobacterium tuberculosis-mediated metabolism of targeted xenobiotics

Drug metabolism is generally associated with liver enzymes. However, in the case of Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), Mtb-mediated drug metabolism plays a significant role in treatment outcomes. Mtb is equipped with enzymes that catalyse biotransformation re...

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Detalles Bibliográficos
Autores principales: Singh, Vinayak, Dziwornu, Godwin Akpeko, Chibale, Kelly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026799/
https://www.ncbi.nlm.nih.gov/pubmed/37117810
http://dx.doi.org/10.1038/s41570-023-00472-3