Exploring novel derivatives of isatin-based Schiff bases as multi-target agents: design, synthesis, in vitro biological evaluation, and in silico ADMET analysis with molecular modeling simulations

Recently, scientists developed a powerful strategy called “one drug-multiple targets” to discover vital and unique therapies to fight the most challenging diseases. Novel derivatives of isatin-based Schiff bases 2–7 have been synthesized by the reaction of 3-hydrazino-isatin (1) with aryl aldehydes,...

Descripción completa

Detalles Bibliográficos
Autores principales: Hassan, Ashraf S., Morsy, Nesrin M., Aboulthana, Wael M., Ragab, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026821/
https://www.ncbi.nlm.nih.gov/pubmed/36950709
http://dx.doi.org/10.1039/d3ra00297g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026821/
https://www.ncbi.nlm.nih.gov/pubmed/36950709
http://dx.doi.org/10.1039/d3ra00297g

Ejemplares similares