Cargando…

Epiblast-like stem cells established by Wnt/β-catenin signaling manifest distinct features of formative pluripotency and germline competence

Different formative pluripotent stem cells harboring similar functional properties have been recently established to be lineage neutral and germline competent yet have distinct molecular identities. Here, we show that WNT/β-catenin signaling activation sustains transient mouse epiblast-like cells as...

Descripción completa

Detalles Bibliográficos
Autores principales: Luo, Qing, Pui, Han-pin, Chen, Jiayu, Yu, Leqian, Jannig, Paulo R., Pei, Yu, Zhao, Linxuan, Chen, Xingqi, Petropoulos, Sophie, Ruas, Jorge L., Wu, Jun, Deng, Qiaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026833/
https://www.ncbi.nlm.nih.gov/pubmed/36848234
http://dx.doi.org/10.1016/j.celrep.2023.112021