Structure-based design of oligomeric receptor-binding domain (RBD) recombinant proteins as potent vaccine candidates against SARS-CoV-2

The receptor-binding domain (RBD) of SARS-CoV-2 S protein is proved to be the major target of neutralizing antibodies. However, on the S protein, only a portion of epitopes in RBD can be effectively displayed with dynamic changes in spatial conformations. Using RBD fragment as antigen can better exp...

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Detalles Bibliográficos
Autores principales: Zhang, Ting, Zheng, Ningchen, Wang, Zhirong, Xu, Xuemei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Coronavirus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026890/
https://www.ncbi.nlm.nih.gov/pubmed/36846890
http://dx.doi.org/10.1080/21645515.2023.2174755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026890/
https://www.ncbi.nlm.nih.gov/pubmed/36846890
http://dx.doi.org/10.1080/21645515.2023.2174755

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