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Dimethyl fumarate protects against hepatic ischemia-reperfusion injury by alleviating ferroptosis via the NRF2/SLC7A11/HO-1 axis

Dimethyl fumarate (DMF), a therapeutic agent for relapsing-remitting multiple sclerosis, has cytoprotective and antioxidant effects. Ferroptosis, a pathological cell death process, is recently shown to play a vital part in ischemia-reperfusion injury (IRI). This study aimed to unveil the suppressive...

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Detalles Bibliográficos
Autores principales: Qi, Debin, Chen, Peng, Bao, Haili, Zhang, Lei, Sun, Keyan, Song, Shaohua, Li, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026899/
https://www.ncbi.nlm.nih.gov/pubmed/36482709
http://dx.doi.org/10.1080/15384101.2022.2155016