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RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease

Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD) architecture in NAFLD. APPROACH AND RESULTS: Functional studies evalua...

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Detalles Bibliográficos
Autores principales: Afonso, Marta B., Islam, Tawhidul, Magusto, Julie, Amorim, Ricardo, Lenoir, Véronique, Simões, Rui F., Teixeira, José, Silva, Liana C., Wendum, Dominique, Jéru, Isabelle, Vigouroux, Corinne, Castro, Rui E., Oliveira, Paulo J., Prip‐Buus, Carina, Ratziu, Vlad, Gautheron, Jérémie, Rodrigues, Cecília M. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026966/
https://www.ncbi.nlm.nih.gov/pubmed/36029129
http://dx.doi.org/10.1002/hep.32756