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EVA1A (Eva-1 Homolog A) Promotes Endothelial Apoptosis and Inflammatory Activation Under Disturbed Flow Via Regulation of Autophagy

Hemodynamic wall shear stress (WSS) exerted on the endothelium by flowing blood determines the spatial distribution of atherosclerotic lesions. Disturbed flow (DF) with a low WSS magnitude and reversing direction promotes atherosclerosis by regulating endothelial cell (EC) viability and function, wh...

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Detalles Bibliográficos
Autores principales: Canham, Lindsay, Sendac, Sam, Diagbouga, Mannekomba R., Wolodimeroff, Elena, Pirri, Daniela, Tardajos Ayllon, Blanca, Feng, Shuang, Souilhol, Celine, Chico, Timothy J.A., Evans, Paul C., Serbanovic-Canic, Jovana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026973/
https://www.ncbi.nlm.nih.gov/pubmed/36794585
http://dx.doi.org/10.1161/ATVBAHA.122.318110