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Measuring hepatitis B pgRNA stability using an updated automated HBV pgRNA assay with increased sensitivity

HBV pregenomic RNA (pgRNA) is a circulating biomarker for covalently closed circular DNA activity in HBV-infected individuals and has been studied for treatment efficacy, disease staging, and off-therapy outcomes; however, data on the stability are scarce. Increasing HBV pgRNA assay sensitivity may...

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Detalles Bibliográficos
Autores principales: Anderson, Mark, Stec, Michael, Thi, Emily P., Picchio, Gaston, Mbanya, Dora, Cloherty, Gavin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027030/
https://www.ncbi.nlm.nih.gov/pubmed/36930867
http://dx.doi.org/10.1097/HC9.0000000000000099