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Silencing of STE20-type kinase TAOK1 confers protection against hepatocellular lipotoxicity through metabolic rewiring

NAFLD has become the leading cause of chronic liver disease worldwide afflicting about one quarter of the adult population. NASH is a severe subtype of NAFLD, which in addition to hepatic steatosis connotes liver inflammation and hepatocyte ballooning. In light of the exponentially increasing preval...

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Detalles Bibliográficos
Autores principales: Xia, Ying, Andersson, Emma, Anand, Sumit K., Cansby, Emmelie, Caputo, Mara, Kumari, Sima, Porosk, Rando, Kilk, Kalle, Nair, Syam, Marschall, Hanns-Ulrich, Blüher, Matthias, Mahlapuu, Margit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027040/
https://www.ncbi.nlm.nih.gov/pubmed/36930872
http://dx.doi.org/10.1097/HC9.0000000000000037