Cargando…
Silencing of STE20-type kinase TAOK1 confers protection against hepatocellular lipotoxicity through metabolic rewiring
NAFLD has become the leading cause of chronic liver disease worldwide afflicting about one quarter of the adult population. NASH is a severe subtype of NAFLD, which in addition to hepatic steatosis connotes liver inflammation and hepatocyte ballooning. In light of the exponentially increasing preval...
Autores principales: | Xia, Ying, Andersson, Emma, Anand, Sumit K., Cansby, Emmelie, Caputo, Mara, Kumari, Sima, Porosk, Rando, Kilk, Kalle, Nair, Syam, Marschall, Hanns-Ulrich, Blüher, Matthias, Mahlapuu, Margit |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027040/ https://www.ncbi.nlm.nih.gov/pubmed/36930872 http://dx.doi.org/10.1097/HC9.0000000000000037 |
Ejemplares similares
-
STE20-type kinase TAOK3 regulates hepatic lipid partitioning
por: Xia, Ying, et al.
Publicado: (2021) -
Inhibition of MAP4K4 signaling initiates metabolic reprogramming to protect hepatocytes from lipotoxic damage
por: Anand, Sumit Kumar, et al.
Publicado: (2022) -
Knockout of STE20-type kinase TAOK3 does not attenuate diet-induced NAFLD development in mice
por: Xia, Ying, et al.
Publicado: (2023) -
STE20‐Type Protein Kinase MST4 Controls NAFLD Progression by Regulating Lipid Droplet Dynamics and Metabolic Stress in Hepatocytes
por: Caputo, Mara, et al.
Publicado: (2021) -
Silencing of STE20-type kinase STK25 in human aortic endothelial and smooth muscle cells is atheroprotective
por: Cansby, Emmelie, et al.
Publicado: (2022)