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MGAE-DC: Predicting the synergistic effects of drug combinations through multi-channel graph autoencoders

Accurate prediction of synergistic effects of drug combinations can reduce the experimental costs for drug development and facilitate the discovery of novel efficacious combination therapies for clinical studies. The drug combinations with high synergy scores are regarded as synergistic ones, while...

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Detalles Bibliográficos
Autores principales: Zhang, Peng, Tu, Shikui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027223/
https://www.ncbi.nlm.nih.gov/pubmed/36867661
http://dx.doi.org/10.1371/journal.pcbi.1010951