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MGAE-DC: Predicting the synergistic effects of drug combinations through multi-channel graph autoencoders
Accurate prediction of synergistic effects of drug combinations can reduce the experimental costs for drug development and facilitate the discovery of novel efficacious combination therapies for clinical studies. The drug combinations with high synergy scores are regarded as synergistic ones, while...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027223/ https://www.ncbi.nlm.nih.gov/pubmed/36867661 http://dx.doi.org/10.1371/journal.pcbi.1010951 |