Live imaging reveals chromatin compaction transitions and dynamic transcriptional bursting during stem cell differentiation in vivo

Stem cell differentiation requires dramatic changes in gene expression and global remodeling of chromatin architecture. How and when chromatin remodels relative to the transcriptional, behavioral, and morphological changes during differentiation remain unclear, particularly in an intact tissue conte...

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Detalles Bibliográficos
Autores principales: May, Dennis, Yun, Sangwon, Gonzalez, David G, Park, Sangbum, Chen, Yanbo, Lathrop, Elizabeth, Cai, Biao, Xin, Tianchi, Zhao, Hongyu, Wang, Siyuan, Gonzalez, Lauren E, Cockburn, Katie, Greco, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Stem Cells and Regenerative Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027315/
https://www.ncbi.nlm.nih.gov/pubmed/36880644
http://dx.doi.org/10.7554/eLife.83444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027315/
https://www.ncbi.nlm.nih.gov/pubmed/36880644
http://dx.doi.org/10.7554/eLife.83444

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