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Dynamics of co-substrate pools can constrain and regulate metabolic fluxes

Cycling of co-substrates, whereby a metabolite is converted among alternate forms via different reactions, is ubiquitous in metabolism. Several cycled co-substrates are well known as energy and electron carriers (e.g. ATP and NAD(P)H), but there are also other metabolites that act as cycled co-subst...

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Detalles Bibliográficos
Autores principales: West, Robert, Delattre, Hadrien, Noor, Elad, Feliu, Elisenda, Soyer, Orkun S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027320/
https://www.ncbi.nlm.nih.gov/pubmed/36799616
http://dx.doi.org/10.7554/eLife.84379