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Non-viral gene coating modified IOL delivering PDGFR-α shRNA interferes with the fibrogenic process to prevent posterior capsular opacification

Posterior capsule opacification (PCO), the most common complication after cataract surgery, is caused by the proliferation, migration and epithelial–mesenchymal transition (EMT) of residual lens epithelial cells in the capsule bag. Although the surface modification and drug loading of intraocular le...

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Detalles Bibliográficos
Autores principales: Wang, Jiahao, Hu, Yulin, Han, Yuemei, Fang, Qiuna, Chen, Zhirong, Wang, Yajia, Zhao, Peiyi, Wang, Hui, Lin, Quankui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027433/
https://www.ncbi.nlm.nih.gov/pubmed/36950659
http://dx.doi.org/10.1093/rb/rbad020