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Non-viral gene coating modified IOL delivering PDGFR-α shRNA interferes with the fibrogenic process to prevent posterior capsular opacification
Posterior capsule opacification (PCO), the most common complication after cataract surgery, is caused by the proliferation, migration and epithelial–mesenchymal transition (EMT) of residual lens epithelial cells in the capsule bag. Although the surface modification and drug loading of intraocular le...
Autores principales: | Wang, Jiahao, Hu, Yulin, Han, Yuemei, Fang, Qiuna, Chen, Zhirong, Wang, Yajia, Zhao, Peiyi, Wang, Hui, Lin, Quankui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027433/ https://www.ncbi.nlm.nih.gov/pubmed/36950659 http://dx.doi.org/10.1093/rb/rbad020 |
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