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Exosome/metformin-loaded self-healing conductive hydrogel rescues microvascular dysfunction and promotes chronic diabetic wound healing by inhibiting mitochondrial fission

Chronic diabetic wounds remain a globally recognized clinical challenge. They occur due to high concentrations of reactive oxygen species and vascular function disorders. A promising strategy for diabetic wound healing is the delivery of exosomes, comprising bioactive dressings. Metformin activates...

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Detalles Bibliográficos
Autores principales: Zhang, Yue, Li, Meng, Wang, Yunchuan, Han, Fei, Shen, Kuo, Luo, Liang, Li, Yan, Jia, Yanhui, Zhang, Jian, Cai, Weixia, Wang, Kejia, Zhao, Ming, Wang, Jing, Gao, Xiaowen, Tian, Chenyang, Guo, Baolin, Hu, Dahai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027478/
https://www.ncbi.nlm.nih.gov/pubmed/36950152
http://dx.doi.org/10.1016/j.bioactmat.2023.01.020