Waldenström macroglobulinemia whole genome reveals prolonged germinal center activity and late copy number aberrations

The genomic landscape of Waldenström macroglobulinemia (WM) is characterized by somatic mutations in MYD88, present from the precursor stages. Using the comprehensive resolution of whole genome sequencing (WGS) in 14 CD19-selected primary WM samples; comparing clonal and subclonal mutations revealed...

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Detalles Bibliográficos
Autores principales: Maclachlan, Kylee H., Bagratuni, Tina, Kastritis, Efstathios, Ziccheddu, Bachisio, Lu, Sydney, Yellapantula, Venkata, Famulare, Chris, Argyropoulos, Kimon, Derkach, Andriy, Papaemmanuil, Elli, Dogan, Ahmet, Lesokhin, Alexander, Usmani, Saad Z., Landgren, C. Ola, Palomba, Lia M., Maura, Francesco, Dimopoulos, Meletios A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Lymphoid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027506/
https://www.ncbi.nlm.nih.gov/pubmed/36332058
http://dx.doi.org/10.1182/bloodadvances.2022008876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027506/
https://www.ncbi.nlm.nih.gov/pubmed/36332058
http://dx.doi.org/10.1182/bloodadvances.2022008876

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