Disordered proteins mitigate the temperature dependence of site-specific binding free energies

Biophysical characterization of protein–protein interactions involving disordered proteins is challenging. A common simplification is to measure the thermodynamics and kinetics of disordered site binding using peptides containing only the minimum residues necessary. We should not assume, however, th...

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Detalles Bibliográficos
Autores principales: Thole, Joseph F., Waudby, Christopher A., Pielak, Gary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027511/
https://www.ncbi.nlm.nih.gov/pubmed/36739945
http://dx.doi.org/10.1016/j.jbc.2023.102984

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027511/
https://www.ncbi.nlm.nih.gov/pubmed/36739945
http://dx.doi.org/10.1016/j.jbc.2023.102984

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