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Disordered proteins mitigate the temperature dependence of site-specific binding free energies
Biophysical characterization of protein–protein interactions involving disordered proteins is challenging. A common simplification is to measure the thermodynamics and kinetics of disordered site binding using peptides containing only the minimum residues necessary. We should not assume, however, th...
Autores principales: | Thole, Joseph F., Waudby, Christopher A., Pielak, Gary J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027511/ https://www.ncbi.nlm.nih.gov/pubmed/36739945 http://dx.doi.org/10.1016/j.jbc.2023.102984 |
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