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Engineered macrophage-biomimetic versatile nanoantidotes for inflammation-targeted therapy against Alzheimer's disease by neurotoxin neutralization and immune recognition suppression

Immune recognition of excessive neurotoxins by microglia is a trigger for the onset of neuroinflammation in the brain, leading to neurodegeneration in Alzheimer's disease (AD). Blocking active recognition of microglia while removing neurotoxins holds promise for fundamentally alleviating neurot...

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Detalles Bibliográficos
Autores principales: Cheng, Meng, Ye, Caihua, Tian, Chunxiao, Zhao, Dongju, Li, Haonan, Sun, Zuhao, Miao, Yuyang, Zhang, Qiang, Wang, Junping, Dou, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027514/
https://www.ncbi.nlm.nih.gov/pubmed/36950153
http://dx.doi.org/10.1016/j.bioactmat.2023.03.004