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Engineered macrophage-biomimetic versatile nanoantidotes for inflammation-targeted therapy against Alzheimer's disease by neurotoxin neutralization and immune recognition suppression
Immune recognition of excessive neurotoxins by microglia is a trigger for the onset of neuroinflammation in the brain, leading to neurodegeneration in Alzheimer's disease (AD). Blocking active recognition of microglia while removing neurotoxins holds promise for fundamentally alleviating neurot...
Autores principales: | Cheng, Meng, Ye, Caihua, Tian, Chunxiao, Zhao, Dongju, Li, Haonan, Sun, Zuhao, Miao, Yuyang, Zhang, Qiang, Wang, Junping, Dou, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027514/ https://www.ncbi.nlm.nih.gov/pubmed/36950153 http://dx.doi.org/10.1016/j.bioactmat.2023.03.004 |
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