Cargando…

Fitm2 is required for ER homeostasis and normal function of murine liver

The endoplasmic reticulum (ER)–resident protein fat storage–inducing transmembrane protein 2 (FIT2) catalyzes acyl-CoA cleavage in vitro and is required for ER homeostasis and normal lipid storage in cells. The gene encoding FIT2 is essential for the viability of mice and worms. Whether FIT2 acts as...

Descripción completa

Detalles Bibliográficos
Autores principales: Bond, Laura M., Ibrahim, Ayon, Lai, Zon W., Walzem, Rosemary L., Bronson, Roderick T., Ilkayeva, Olga R., Walther, Tobias C., Farese, Robert V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027564/
https://www.ncbi.nlm.nih.gov/pubmed/36805337
http://dx.doi.org/10.1016/j.jbc.2023.103022