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Frozen fresh blood plasma preserves the functionality of native human α(2)-macroglobulin
Human α(2)-macroglobulin (hα(2)M) is a large homotetrameric protein involved in the broad inhibition of endopeptidases. Following cleavage within a bait region, hα(2)M undergoes stepwise transitions from its native, expanded, highly flexible, active conformation to an induced, compact, triggered con...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027685/ https://www.ncbi.nlm.nih.gov/pubmed/36941303 http://dx.doi.org/10.1038/s41598-023-31800-8 |