Cargando…
Frozen fresh blood plasma preserves the functionality of native human α(2)-macroglobulin
Human α(2)-macroglobulin (hα(2)M) is a large homotetrameric protein involved in the broad inhibition of endopeptidases. Following cleavage within a bait region, hα(2)M undergoes stepwise transitions from its native, expanded, highly flexible, active conformation to an induced, compact, triggered con...
Autores principales: | Mendes, Soraia R., Gomis-Rüth, F. Xavier, Goulas, Theodoros |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027685/ https://www.ncbi.nlm.nih.gov/pubmed/36941303 http://dx.doi.org/10.1038/s41598-023-31800-8 |
Ejemplares similares
-
Reply to Harwood et al.: Alternative functional conformations of native human α(2)-macroglobulin
por: Luque, Daniel, et al.
Publicado: (2022) -
Cryo-EM structures show the mechanistic basis of pan-peptidase inhibition by human α(2)-macroglobulin
por: Luque, Daniel, et al.
Publicado: (2022) -
Recombinant production of human α(2)-macroglobulin variants and interaction studies with recombinant G-related α(2)-macroglobulin binding protein and latent transforming growth factor-β(2)
por: Marino-Puertas, Laura, et al.
Publicado: (2019) -
An audit of fresh frozen plasma usage and effect of fresh frozen plasma on the pre–transfusion international normalized ratio
por: Shinagare, S. A., et al.
Publicado: (2010) -
Analysis of the inhibiting activity of reversion-inducing cysteine-rich protein with Kazal motifs (RECK) on matrix metalloproteinases
por: Mendes, Soraia R., et al.
Publicado: (2020)