Insights into the mechanisms of triptolide nephrotoxicity through network pharmacology-based analysis and RNA-seq

INTRODUCTION: Triptolide (TPL) is a promising plant-derived compound for clinical therapy of multiple human diseases; however, its application was limited considering its toxicity. METHODS: To explore the underlying molecular mechanism of TPL nephrotoxicity, a network pharmacology based approach was...

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Detalles Bibliográficos
Autores principales: Luo, Yue-Ming, Yang, Shu-Dong, Wen, Miao-Yu, Wang, Bing, Liu, Jia-Hui, Li, Si-Ting, Li, Yu-Yan, Cheng, Hong, Zhao, Li-Li, Li, Shun-Min, Jiang, Jian-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Plant Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027700/
https://www.ncbi.nlm.nih.gov/pubmed/36959927
http://dx.doi.org/10.3389/fpls.2023.1144583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027700/
https://www.ncbi.nlm.nih.gov/pubmed/36959927
http://dx.doi.org/10.3389/fpls.2023.1144583

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