Inhibiting efferocytosis reverses macrophage-mediated immunosuppression in the leukemia microenvironment

BACKGROUND: Previous studies show that the spleen and bone marrow can serve as leukemia microenvironments in which macrophages play a significant role in immune evasion and chemoresistance. We hypothesized that the macrophage driven tolerogenic process of efferocytosis is a major contributor to the...

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Detalles Bibliográficos
Autores principales: Cruz Cruz, Joselyn, Allison, Kristen C., Page, Lauren S., Jenkins, Alexis J., Wang, Xiaodong, Earp, H. Shelton, Frye, Stephen V., Graham, Douglas K., Verneris, Michael R., Lee-Sherick, Alisa B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027704/
https://www.ncbi.nlm.nih.gov/pubmed/36960055
http://dx.doi.org/10.3389/fimmu.2023.1146721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027704/
https://www.ncbi.nlm.nih.gov/pubmed/36960055
http://dx.doi.org/10.3389/fimmu.2023.1146721

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