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Natural and engineered mediators of desiccation tolerance stabilize Human Blood Clotting Factor VIII in a dry state

Biologics, pharmaceuticals containing or derived from living organisms, such as vaccines, antibodies, stem cells, blood, and blood products are a cornerstone of modern medicine. However, nearly all biologics have a major deficiency: they are inherently unstable, requiring storage under constant cold...

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Detalles Bibliográficos
Autores principales: Packebush, Maxwell H., Sanchez-Martinez, Silvia, Biswas, Sourav, KC, Shraddha, Nguyen, Kenny H., Ramirez, John F., Nicholson, Vincent, Boothby, Thomas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027729/
https://www.ncbi.nlm.nih.gov/pubmed/36941331
http://dx.doi.org/10.1038/s41598-023-31586-9