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Conditional deletion of Neurexin-2 alters neuronal network activity in hippocampal circuitries and leads to spontaneous seizures

Neurexins (Nrxns) have been extensively studied for their role in synapse organization and have been linked to many neuropsychiatric disorders, including autism spectrum disorder (ASD), and epilepsy. However, no studies have provided direct evidence that Nrxns may be the key regulator in the shared...

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Detalles Bibliográficos
Autores principales: Haile, Mulatwa T., Khoja, Sheraz, de Carvalho, Gregory, Hunt, Robert F., Chen, Lulu Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027846/
https://www.ncbi.nlm.nih.gov/pubmed/36941261
http://dx.doi.org/10.1038/s41398-023-02394-6