Mitochondrial dysfunction rapidly modulates the abundance and thermal stability of cellular proteins

Cellular functionality relies on a well-balanced, but highly dynamic proteome. Dysfunction of mitochondrial protein import leads to the cytosolic accumulation of mitochondrial precursor proteins which compromise cellular proteostasis and trigger a mitoprotein-induced stress response. To dissect the...

Descripción completa

Detalles Bibliográficos
Autores principales: Groh, Carina, Haberkant, Per, Stein, Frank, Filbeck, Sebastian, Pfeffer, Stefan, Savitski, Mikhail M, Boos, Felix, Herrmann, Johannes M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027898/
https://www.ncbi.nlm.nih.gov/pubmed/36941057
http://dx.doi.org/10.26508/lsa.202201805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027898/
https://www.ncbi.nlm.nih.gov/pubmed/36941057
http://dx.doi.org/10.26508/lsa.202201805

Ejemplares similares