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A plant-produced SARS-CoV-2 spike protein elicits heterologous immunity in hamsters

Molecular farming of vaccines has been heralded as a cheap, safe and scalable production platform. In reality, however, differences in the plant biosynthetic machinery, compared to mammalian cells, can complicate the production of viral glycoproteins. Remodelling the secretory pathway presents an op...

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Detalles Bibliográficos
Autores principales: Margolin, Emmanuel, Schäfer, Georgia, Allen, Joel D., Gers, Sophette, Woodward, Jeremy, Sutherland, Andrew D., Blumenthal, Melissa, Meyers, Ann, Shaw, Megan L., Preiser, Wolfgang, Strasser, Richard, Crispin, Max, Williamson, Anna-Lise, Rybicki, Edward P., Chapman, Ros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028082/
https://www.ncbi.nlm.nih.gov/pubmed/36959936
http://dx.doi.org/10.3389/fpls.2023.1146234