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The prevalence of gene mutations in homologous recombination repair pathways in Japanese patients with metastatic castration‐resistant prostate cancer in real‐world clinical practice: The multi‐institutional observational ZENSHIN study

BACKGROUND: Metastatic castration‐resistant prostate cancer (mCRPC) is a genetically heterogeneous disease with a poor prognosis. The prevalence of mutations in homologous recombination repair (HRR) pathway genes, including BRCA1/2, as well as treatment patterns and clinical outcomes, are not well c...

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Detalles Bibliográficos
Autores principales: Uemura, Hiroji, Oya, Mototsugu, Kamoto, Toshiyuki, Sugimoto, Mikio, Shinozaki, Kenta, Morita, Kiyomi, Koto, Ryo, Takahashi, Mai, Nii, Masahiro, Shin, Eisei, Nonomura, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028105/
https://www.ncbi.nlm.nih.gov/pubmed/36358026
http://dx.doi.org/10.1002/cam4.5333