Regulation of DNA‐PK activity promotes the progression of TNBC via enhancing the immunosuppressive function of myeloid‐derived suppressor cells

BACKGROUND: DNA‐dependent protein kinase (DNA‐PK) is engaged in DNA damage repair and is significantly expressed in triple negative breast cancer (TNBC). Inhibiting DNA‐PK to reduce DNA damage repair provides a possibility of tumor treatment. NU7441, a DNA‐PK inhibitor, can regulate the function and...

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Detalles Bibliográficos
Autores principales: Han, Jiawen, Wan, Minjie, Ma, Zhanchuan, Yi, Huanfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
RESEARCH ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028116/
https://www.ncbi.nlm.nih.gov/pubmed/36373232
http://dx.doi.org/10.1002/cam4.5387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028116/
https://www.ncbi.nlm.nih.gov/pubmed/36373232
http://dx.doi.org/10.1002/cam4.5387

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