cGAS-dependent proinflammatory and immune homeostatic effects of the microtubule-targeting agent paclitaxel

Taxanes are Microtubule-Targeting Agents (MTAs) that exert potent anticancer activity by directly killing cancer cells. However, recent evidence suggests that they may also stimulate inflammation and anticancer adaptive immunity and that these actions strongly contribute to their therapeutic efficac...

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Detalles Bibliográficos
Autores principales: Serpico, Angela Flavia, Pisauro, Caterina, Grieco, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028148/
https://www.ncbi.nlm.nih.gov/pubmed/36960066
http://dx.doi.org/10.3389/fimmu.2023.1127623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028148/
https://www.ncbi.nlm.nih.gov/pubmed/36960066
http://dx.doi.org/10.3389/fimmu.2023.1127623

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