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cGAS-dependent proinflammatory and immune homeostatic effects of the microtubule-targeting agent paclitaxel
Taxanes are Microtubule-Targeting Agents (MTAs) that exert potent anticancer activity by directly killing cancer cells. However, recent evidence suggests that they may also stimulate inflammation and anticancer adaptive immunity and that these actions strongly contribute to their therapeutic efficac...
Autores principales: | Serpico, Angela Flavia, Pisauro, Caterina, Grieco, Domenico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028148/ https://www.ncbi.nlm.nih.gov/pubmed/36960066 http://dx.doi.org/10.3389/fimmu.2023.1127623 |
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