Combined flow cytometry natural killer immunophenotyping and KIR/HLA-C genotyping reveal remarkable differences in acute myeloid leukemia patients, but suggest an overall impairment of the natural killer response

INTRODUCTION: Natural killer (NK) cells are key anti-tumor effectors of the innate immunity. Phenotypic differences allow us to discriminate in between three functional stages of maturation, named immature, mature and hypermature that are distinctive in terms of receptor expression, cytokine secreti...

Descripción completa

Detalles Bibliográficos
Autores principales: Cianga, Vlad Andrei, Rusu, Cristina, Pavel-Tanasa, Mariana, Dascalescu, Angela, Danaila, Catalin, Harnau, Sebastian, Aanei, Carmen-Mariana, Cianga, Petru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028202/
https://www.ncbi.nlm.nih.gov/pubmed/36960339
http://dx.doi.org/10.3389/fmed.2023.1148748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028202/
https://www.ncbi.nlm.nih.gov/pubmed/36960339
http://dx.doi.org/10.3389/fmed.2023.1148748

Ejemplares similares