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Cladribine treatment specifically affects peripheral blood memory B cell clones and clonal expansion in multiple sclerosis patients

INTRODUCTION: B cells are acknowledged as crucial players in the pathogenesis of multiple sclerosis (MS). Several disease modifying drugs including cladribine have been shown to exert differential effects on peripheral blood B cell subsets. However, little is known regarding functional changes withi...

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Detalles Bibliográficos
Autores principales: Ruschil, Christoph, Gabernet, Gisela, Kemmerer, Constanze Louisa, Jarboui, Mohamed Ali, Klose, Franziska, Poli, Sven, Ziemann, Ulf, Nahnsen, Sven, Kowarik, Markus Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028280/
https://www.ncbi.nlm.nih.gov/pubmed/36960053
http://dx.doi.org/10.3389/fimmu.2023.1133967