The efficacy and safety of SARS-CoV-2 vaccines mRNA1273 and BNT162b2 might be complicated by rampant C-to-U RNA editing

The SARS-CoV-2 RNA vaccines are smartly designed to increase the synonymous codon usage by introducing multiple U-to-C mutations. This design would elevate the translation efficiency of vaccine RNAs. However, we found evidence to reason that the designed cytidines might be converted to uridines agai...

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Detalles Bibliográficos
Autores principales: Bian, Zhongzheng, Wu, Ziqian, Liu, Nan, Jiang, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Microbial Genetics • Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028319/
https://www.ncbi.nlm.nih.gov/pubmed/36943642
http://dx.doi.org/10.1007/s13353-023-00756-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028319/
https://www.ncbi.nlm.nih.gov/pubmed/36943642
http://dx.doi.org/10.1007/s13353-023-00756-w

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