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The efficacy and safety of SARS-CoV-2 vaccines mRNA1273 and BNT162b2 might be complicated by rampant C-to-U RNA editing
The SARS-CoV-2 RNA vaccines are smartly designed to increase the synonymous codon usage by introducing multiple U-to-C mutations. This design would elevate the translation efficiency of vaccine RNAs. However, we found evidence to reason that the designed cytidines might be converted to uridines agai...
Autores principales: | Bian, Zhongzheng, Wu, Ziqian, Liu, Nan, Jiang, Xiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028319/ https://www.ncbi.nlm.nih.gov/pubmed/36943642 http://dx.doi.org/10.1007/s13353-023-00756-w |
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