Tuning anticancer properties and DNA-binding of Pt(ii) complexes via alteration of nitrogen softness/basicity of tridentate ligands

Nine tridentate Schiff base ligands of the type (N^N^O) were synthesized from reactions of primary amines {2-picolylamine (Py), N-phenyl-1,2-diaminobenzene (PhN), and N-phenyl-1,2-diaminoethane(EtN)} and salicylaldehyde derivatives {3-ethoxy (OEt), 4-diethylamine (NEt(2)) and 4-hydroxy (OH)}. Comple...

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Detalles Bibliográficos
Autores principales: Al-Rashdi, Kamelah S., Babgi, Bandar A., Ali, Ehab M. M., Jedidi, Abdesslem, Emwas, Abdul-Hamid M., Davaasuren, Bambar, Jaremko, Mariusz, Humphrey, Mark G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028500/
https://www.ncbi.nlm.nih.gov/pubmed/36959884
http://dx.doi.org/10.1039/d3ra00395g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028500/
https://www.ncbi.nlm.nih.gov/pubmed/36959884
http://dx.doi.org/10.1039/d3ra00395g

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