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Isothiouronium-Mediated Conversion of Carboxylic Acids to Cyanomethyl Thioesters
[Image: see text] We report the development of an isothiouronium salt as a reagent for the operationally simple synthesis of cyanomethyl thioesters with high functional group tolerance and avoiding the use of thiols. Additionally, we show that the products can be engaged in amide synthesis in either...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028607/ https://www.ncbi.nlm.nih.gov/pubmed/36853206 http://dx.doi.org/10.1021/acs.joc.2c02902 |