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Short Activators and Repressors of RNA Toehold Switches

[Image: see text] RNA toehold switches are a widely used class of molecule to detect specific RNA “trigger” sequences, but their design, intended function, and characterization to date leave it unclear whether they can function properly with triggers shorter than 36 nucleotides. Here, we explore the...

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Detalles Bibliográficos
Autores principales: McSweeney, Megan A., Zhang, Yan, Styczynski, Mark P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028691/
https://www.ncbi.nlm.nih.gov/pubmed/36802167
http://dx.doi.org/10.1021/acssynbio.2c00641