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Differential allelic representation (DAR) identifies candidate eQTLs and improves transcriptome analysis

In comparisons between mutant and wild-type genotypes, transcriptome analysis can reveal the direct impacts of a mutation, together with the homeostatic responses of the biological system. Recent studies have highlighted that, when homozygous mutations are studied in non-isogenic backgrounds, genes...

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Detalles Bibliográficos
Autores principales: Baer, Lachlan, Barthelson, Karissa, Postlethwait, John, Adelson, David, Pederson, Stephen, Lardelli, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028786/
https://www.ncbi.nlm.nih.gov/pubmed/36945478
http://dx.doi.org/10.1101/2023.03.02.530865