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Tigerfish designs oligonucleotide-based in situ hybridization probes targeting intervals of highly repetitive DNA at the scale of genomes

Fluorescent in situ hybridization (FISH) is a powerful method for the targeted visualization of nucleic acids in their native contexts. Recent technological advances have leveraged computationally designed oligonucleotide (oligo) probes to interrogate >100 distinct targets in the same sample, pus...

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Detalles Bibliográficos
Autores principales: Aguilar, Robin, Camplisson, Conor K., Lin, Qiaoyi, Miga, Karen H., Noble, William S., Beliveau, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028787/
https://www.ncbi.nlm.nih.gov/pubmed/36945528
http://dx.doi.org/10.1101/2023.03.06.530899