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Cellos: High-throughput deconvolution of 3D organoid dynamics at cellular resolution for cancer pharmacology

Three-dimensional (3D) culture models, such as organoids, are flexible systems to interrogate cellular growth and morphology, multicellular spatial architecture, and cell interactions in response to drug treatment. However, new computational methods to segment and analyze 3D models at cellular resol...

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Detalles Bibliográficos
Autores principales: Mukashyaka, Patience, Kumar, Pooja, Mellert, David J., Nicholas, Shadae, Noorbakhsh, Javad, Brugiolo, Mattia, Anczukow, Olga, Liu, Edison T., Chuang, Jeffrey H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028797/
https://www.ncbi.nlm.nih.gov/pubmed/36945601
http://dx.doi.org/10.1101/2023.03.03.531019