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Cellos: High-throughput deconvolution of 3D organoid dynamics at cellular resolution for cancer pharmacology
Three-dimensional (3D) culture models, such as organoids, are flexible systems to interrogate cellular growth and morphology, multicellular spatial architecture, and cell interactions in response to drug treatment. However, new computational methods to segment and analyze 3D models at cellular resol...
Autores principales: | Mukashyaka, Patience, Kumar, Pooja, Mellert, David J., Nicholas, Shadae, Noorbakhsh, Javad, Brugiolo, Mattia, Anczukow, Olga, Liu, Edison T., Chuang, Jeffrey H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028797/ https://www.ncbi.nlm.nih.gov/pubmed/36945601 http://dx.doi.org/10.1101/2023.03.03.531019 |
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