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Human Cytomegalovirus Induces Significant Structural and Functional Changes in Terminally Differentiated Human Cortical Neurons

Human cytomegalovirus (HCMV) is a highly prevalent viral pathogen that typically presents asymptomatically in healthy individuals despite lifelong latency. However, in 10–15% of congenital cases, this beta-herpesvirus demonstrates direct effects on the central nervous system, including microcephaly,...

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Detalles Bibliográficos
Autores principales: Adelman, Jacob W., Rosas-Rogers, Suzette, Schumacher, Megan L., Mokry, Rebekah L., Terhune, Scott S., Ebert, Allison D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028818/
https://www.ncbi.nlm.nih.gov/pubmed/36945635
http://dx.doi.org/10.1101/2023.03.03.531045